Pediatric anesthesia & critical care
Effect of paediatric caudal injection volume on optic nerve sheath diameter and regional cerebral oximetry: A randomised trial
Authors' conclusion
Caudal injection with 1.25 ml kg -1 increased ONSD, an indirect measurement of ICP, more than 0.8 ml kg -1 and neither volume caused a clinically important reduction in CrSO 2 .
Study context
- Population
- Elective paediatric surgical patients aged 1–7 years, ASA I or II, without previous intracranial or ocular pathology, suitable for single-shot caudal anaesthesia
- Participants
- 58 patients
- Comparison
- Caudal injection volume 1.25 vs 0.8 ml kg −1
- Ln = 29reference
- Hn = 29
- Primary endpoint
- ONSD (ultrasonography) and CrSO 2 (NIRS)
- Follow-up
- Before, immediately after, 10, 20 and 30 min after the block
Methodological detailsprospective, parallel group
- Prospective
- Parallel group
Primary result
As reported in the abstract
ONSD
| Group | Value | Baseline | Time of maximum |
|---|---|---|---|
| L | mean 4.5 (SD 0.2) mm | 4.4 ± 0.2 mm | 20 min |
| H | mean 4.8 (SD 0.3) mm | 4.5 ± 0.3 mm | 10 min |
Value
Lmean 4.5 (SD 0.2) mm
Hmean 4.8 (SD 0.3) mm
Baseline
L4.4 ± 0.2 mm
H4.5 ± 0.3 mm
Time of maximum
L20 min
H10 min
Further findings
Events
| Outcome | L | H |
|---|---|---|
| ONSD increase >10% | 0 | 8 |
- Optic nerve sheath diameter (ONSD) increase >10%: 8 of 29 in H
CrSO 2
- Both groups had a reduction of less than 2.5% in CrSO 2
Original publication
Effect of paediatric caudal injection volume on optic nerve sheath diameter and regional cerebral oximetry: A randomised trial. Eur J Anaesthesiol. Published 20 March 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →