Cardiothoracic & vascular anesthesia
Association between regional oxygen saturation and central venous saturation in pediatric patients undergoing cardiac surgery: A prospective observational study
Authors' conclusion
Cerebral rSO2 , SpO2 , and BNP were significantly correlated with ScvO2 , although the cerebral rSO2 correlation was greater for lesions without atrial mixing.
Study context
- Population
- Children (weight < 10 kg) undergoing cardiac surgery for congenital heart disease, February 2018 to November 2021
- Participants
- 33 children
- Exposure
- Cerebral and somatic rSO2 vs ScvO2
- Outcome
- Correlation and agreement (Pearson's correlation, Bland-Altman) between rSO2 and ScvO2
- Follow-up
- After anesthesia induction and central venous catheter placement
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Correlation with ScvO2
Bland-Altman bias
0.27 %
95% CI −4.26 to 4.80
Cerebral rSO2 · limits of agreement −24.79 [−32.61 to −16.96] to 25.33 [17.50 to 33.16]
Bland-Altman bias
0.91 %
95% CI −5.48 to 7.30
Somatic rSO2 · limits of agreement −34.43 [−45.47 to −23.39] to 36.25 [25.21 to 47.29]
Cerebral rSO2
- r2 (all patients)
- 0.29
- P (all patients)
- p = .002
- r2 (without mixing at the atrial level)
- 0.61
- P (without mixing at the atrial level)
- p = .013
Cerebral rSO2
r2 (all patients)0.29
P (all patients)p = .002
r2 (without mixing at the atrial level)0.61
P (without mixing at the atrial level)p = .013
Observational data: associations, not effects.
Further findings
Independent variables associated with ScvO2 and cerebral and somatic rSO2 (multiple regression)
- Preoperative brain natriuretic peptide (BNP) and SpO2 independently associated with ScvO2 and cerebral and somatic rSO2
Original publication
Association between regional oxygen saturation and central venous saturation in pediatric patients undergoing cardiac surgery: A prospective observational study. Paediatr Anaesth. Published 3 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →