Cardiothoracic & vascular anesthesia
Associations between baseline cerebral oxygen saturation, preoperative B-type natriuretic peptide and hemoglobin levels, and mortality after cardiac surgery in non-dialysis patients
Authors' conclusion
For all NIRS-derived indicators examined, baseline NIRS values before anesthesia and SmvO₂ values after induction of anesthesia were primarily correlated with BNP and hemoglobin levels. In addition, baseline NIRS values showed a significant association with postoperative in-hospital mortality
Study context
- Population
- Non-dialysis adults undergoing cardiac surgery; Near-infrared spectroscopy (NIRS) measured on forehead before anaesthesia, SmvO₂ after induction
- Participants
- 510 / 468 / 510
- Exposure
- rSO₂ vs tissue oxygenation index (TOI) vs StO₂
- rSO₂ (INVOS 5100C)n = 510
- TOI (NIRO-200NX)n = 468
- StO₂ (FORESIGHT Elite)n = 510
- Outcome
- Correlations of baseline NIRS values and SmvO₂ with 37 preoperative blood test variables; association of baseline NIRS values with postoperative in-hospital mortality
Main finding
As reported in the abstract
Correlation with preoperative blood tests and association with in-hospital mortality
- Baseline NIRS and SmvO₂ values most significantly correlated with BNP and hemoglobin, all three devices
- p < 0.00001
- Baseline rSO₂ associated with postoperative mortality
- p = 0.00101
- Baseline TOI associated with postoperative mortality
- 0.00111
- Baseline StO₂ associated with postoperative mortality
- 0.01122
Observational data: associations, not effects.
Original publication
Associations between baseline cerebral oxygen saturation, preoperative B-type natriuretic peptide and hemoglobin levels, and mortality after cardiac surgery in non-dialysis patients. J Clin Monit Comput. Published 7 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →