Cardiothoracic & vascular anesthesia
Continuous and Noninvasive Total Blood Hemoglobin Measurement Using Near-Infrared Reflectance Spectrometry
Authors' conclusion
The exploratory study shows that the NIRS based tHb provided an accurate measurement of tHb in cardiac surgery patients.
Study context
- Population
- Cardiac surgery patientsincluded in the analysis
- Participants
- 189 patients
- Comparison
- Near-infrared reflectance spectroscopy (NIRS)-based continuous total hemoglobin (tHb) vs blood gas tHb
Methodological detailspost hoc retrospective analysis, multicentre (3 clinical sites), exploratory
- Post hoc retrospective analysis
- Multicentre (3 clinical sites)
- Exploratory
Primary result
As reported in the abstract
Agreement of NIRS-based tHb vs blood gas tHb
- Bias (mean difference), g/dL
- 0.08 (95% CI 0.02-0.19)
- Precision (1 SD of the difference), g/dL
- 1.01 (95% CI 0.93-1.09)
- Limits of agreement, g/dL
- −1.90 and 2.06
- Mean absolute error (MAE), g/dL (0.69-0.91)
- 0.79
- Root mean square error (RMSE), g/dL (0.94-1.30)
- 1.12
- 4-quadrant concordance, % (79.8-92.1)
- 86.1
- Error-grid: measurements in green zone
- 84%
- Error-grid: measurements in red zone
- 0%
Original publication
Continuous and Noninvasive Total Blood Hemoglobin Measurement Using Near-Infrared Reflectance Spectrometry. Anesth Analg. Published 2 July 2025. doi:10.
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