Pediatric anesthesia & critical care

Effect of tidal volume change on pressure‐based prediction of fluid responsiveness in children

Paediatr AnaesthPublished Prospective diagnostic accuracy study

Authors' conclusion

Augmented pulse pressure variation or systolic pressure variation due to increased tidal volume cannot predict fluid responsiveness in children after simple cardiac surgery.

Study context

Population
Children <7 years after cardiac surgery for atrial or ventricular septal defect15 responders
Participants
26 children
Comparison
PPV vs SPV at increased tidal volume for predicting fluid responsiveness
Outcome
Predictability of pulse pressure variation and systolic pressure variation for fluid responsiveness (AUC of ROC curve)

Performance

As reported in the abstract

AUC of ROC curve at tidal volume 14 mL/kg
Test or modelAUCp
Pulse pressure variation0.576p = .517
Systolic pressure variation0.548p = .678

AUC

Pulse pressure variation0.576
Systolic pressure variation0.548

p

Pulse pressure variationp = .517
Systolic pressure variationp = .678

Further findings

Dynamic parameters, responders vs nonresponders

Differences not significant

Original publication

Effect of tidal volume change on pressure‐based prediction of fluid responsiveness in children. Paediatr Anaesth. Published 28 August 2023. doi:10.1111/pan.14751

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