Regional anesthesia

Effect of virtual reality (VR) therapy on pain sensation in patients undergoing hand surgery under ultrasound-guided regional anesthesia: a randomized controlled trial

Reg Anesth Pain MedPublished Randomised controlled trial

Primary resultResult — go to the resultMean difference −0.3 95% CI −1.2 to 0.5

Authors' conclusion

Our results show that the use of virtual reality therapy during ultrasound-guided regional anesthesia placement and hand surgery does not result in lower pain scores.

Study context

Population
Patients undergoing elective hand surgery under ultrasound-guided RA
Participants
120 patients
Comparison
Perioperative VR therapy vs no VR therapy
Primary endpoint
Mean pain score (11-point NRS) during ultrasound-guided RA placement
Methodological detailsprospective, superiority
  • Prospective
  • Superiority

Primary result

As reported in the abstract

Mean difference

−0.3

95% CI −1.2 to 0.5

P = 0.22

By group

Control

3.9

mean · SD 2.4

Virtual reality

3.6

mean · SD 2.4

Virtual reality vs Control
mean difference −0.3 (95% CI −1.2 to 0.5); P = 0.22

Secondary outcomes

OutcomeValuesP value
Anxiety during surgery (NRS)Virtual reality vs ControlControl 1.5 (interval 0.0–4.0) · Virtual reality 0.0 (interval 0.0–2.0)P < 0.01
VR immersion (Igroup Presence Questionnaire)Virtual reality mean 4.2 (SD 0.9)
Satisfaction with VR (NRS)Virtual reality 9.0 (interval 8.0–10.0)

Heart rate variation during RA placement and surgery

Non-significantly different

Anxiety during RA placement

No significant difference

Patient satisfaction during surgery and perioperative opioid use

No significant difference

Safety

OutcomeValues
Adverse VR effectsVirtual reality 11.9%

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Effect of virtual reality (VR) therapy on pain sensation in patients undergoing hand surgery under ultrasound-guided regional anesthesia: a randomized controlled trial. Reg Anesth Pain Med. Published 1 June 2025. doi:10.1136/rapm-2025-106418

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