Perioperative medicine & outcomes
Effect of perioperative rehabilitation exercise on postoperative outcomes in patients aged ≥65 years undergoing gastrointestinal surgery: A multicenter randomized controlled trial
Primary result · 30-day CCIResult — go to the resultβ −6.31 95 % CI −11.26 to −1.37Authors' conclusion
Perioperative rehabilitation exercise has a positive impact on postoperative complications, quality of life and psychological well-being in elderly patients undergoing gastrointestinal surgery, even when implemented after hospital admission.
Study context
- Population
- Patients ≥65 years scheduled for gastrointestinal surgery, June 2021–November 2022
- Participants
- 160 patients
- Comparison
- Perioperative rehabilitation exercise vs control
- Primary endpoint
- Comprehensive Complications Index (CCI)
- Follow-up
- 30 days after surgery
Methodological detailsprospective, multicentre, open-label, assessor-blinded
- Prospective
- Multicentre
- Open-label
- Assessor-blinded
Primary result
30-day CCI
β
−6.31
95 % CI −11.26 to −1.37
P = 0.013
As reported in the abstract
Secondary outcomes
| Outcome | Estimate | P value |
|---|---|---|
| Hospital readmission | OR 0.00 (95 % CI 0.00–0.32) | P = 0.022 |
| Number of complications | β −0.57 (95 % CI −1.03 to −0.11) | P = 0.016 |
| Postoperative anxiety | β −0.74 (95 % CI −1.42 to −0.06) | P = 0.033 |
| Depression scores | β −1.13 (95 % CI −0.97 to −1.30) | P = 0.008 |
| Patient satisfaction | β 0.98 (95 % CI 0.33–1.64) | P = 0.004 |
| EuroQoL VAS score | β 8.88 (95 % CI 2.48–15.28) | P = 0.007 |
Original publication
Effect of perioperative rehabilitation exercise on postoperative outcomes in patients aged ≥65 years undergoing gastrointestinal surgery: A multicenter randomized controlled trial. J Clin Anesth. Published 2 November 2024. doi:10.
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