Effect of transversus abdominis plane block versus intravenous hydromorphone on the quality of postoperative recovery in elderly critically Ill patients in the SICU: a single-center, single-blind, randomised controlled trial
Authors' conclusion
TAP block significantly improves recovery quality and provides better analgesia than hydromorphone in elderly critically ill patients after major abdominal surgery, reducing opioid use and enhancing postoperative outcomes.
Study context
- Population
- Elderly critically ill patients after major abdominal surgery in the Surgical ICU with postoperative pain (VAS ≥ 4), Jiaxing First Hospital, July 2024 to December 2025122 completed
- Participants
- 61 vs 61
- Comparison
- Ultrasound-guided TAP block vs IV hydromorphone
- TAPn = 61
- Controln = 61reference
- Primary endpoint
- Quality of Recovery-40 (QoR-40) score
- Follow-up
- 24 h postoperatively
Methodological detailsprospective, single-blind, single-centre
- Prospective
- Single-blind
- Single-centre
Primary result
As reported in the abstract
QoR-40 score · 24 h
TAP
170
median · IQR 167–172
Control
157
median · IQR 153–158
P < 0.001
Secondary outcomes
Median
| Outcome | TAP | Control | P value |
|---|---|---|---|
| QoR-40 score · 48 hAbstract states significantly higher in TAP | 162 (IQR 159,165) | 171 (IQR 169,174) | P < 0.001 |
- QoR-40 score: values in the order printed; inconsistent with the stated direction
VAS scores and opioid consumption
- Lower VAS scores and reduced opioid consumption in TAP vs Control
Original publication
Effect of transversus abdominis plane block versus intravenous hydromorphone on the quality of postoperative recovery in elderly critically Ill patients in the SICU: a single-center, single-blind, randomised controlled trial. Perioper Med (Lond). Published 27 November 2025. doi:10.
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