Perioperative medicine & outcomes
Effect of ventilation mode on postoperative pulmonary complications among intermediate- to high-risk patients undergoing abdominal surgery: A randomized controlled trial
Authors' conclusion
In intermediate- to high-risk patients undergoing abdominal surgery, the choice of ventilation mode did not affect the risk of PPCs.
Study context
- Population
- Adults at intermediate or high risk of postoperative pulmonary complications (PPCs) scheduled for abdominal surgery; lung-protective ventilation in all groups1,349 analysed
- Participants
- 1,365 adults
- Comparison
- Volume-controlled ventilation (VCV) vs pressure-controlled ventilation (PCV) vs PCV-VG
- Primary endpoint
- Composite of pulmonary complications
- Follow-up
- First 7 postoperative days
Primary result
As reported in the abstract
P = 0.865
Secondary outcomes
Pulmonary complications within 30 postoperative days, severity grade of PPCs, other secondary outcomes
- No statistically significant differences among the three groups
Original publication
Effect of ventilation mode on postoperative pulmonary complications among intermediate- to high-risk patients undergoing abdominal surgery: A randomized controlled trial. Anaesth Crit Care Pain Med. Published 13 September 2024. doi:10. 1016/ j. accpm. 2024. 101423
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