Pain medicine

Effectiveness of multimodal analgesia on surgically treated geriatric hip fracture patients: a propensity score matching analysis

Reg Anesth Pain MedPublished Retrospective cohort study

Authors' conclusion

Our findings showed that implementing a multimodal analgesia protocol for hip fracture surgery was associated with lower postoperative pain and reduced opioid consumption

Study context

Population
Patients undergoing surgery for hip fracture (femoral neck, intertrochanteric, subtrochanteric), single institution, 2008–2023matched cohort
Participants
280 vs 280
Exposure
Standardised multimodal analgesia protocol vs no multimodal analgesia
  • Multimodal analgesian = 280
  • Controln = 280reference
Outcome
Pain scores (VAS at 6, 12, 24 and 48 h postoperatively) and oral opioid use
Follow-up
Within 48 hours postoperatively
Methodological detailspropensity-score matched 1:1, single-centre, historical control, 2019–2021 excluded as transition period
  • Propensity-score matched 1:1
  • Single-centre
  • Historical control
  • 2019–2021 excluded as transition period

Main finding

As reported in the abstract

Multimodal analgesia
VAS pain score at 6 h 1.9 vs 2.9; P < 0.001
Multimodal analgesia
VAS pain score at 24 h 2.0 vs 2.4; P = 0.001
Multimodal analgesia
VAS pain score at 48 h 1.7 vs 2.2; P < 0.001
Multimodal analgesia
48-h opioid usage 5.5 vs 13.3 mg; P = 0.014

Observational data: associations, not effects.

Original publication

Effectiveness of multimodal analgesia on surgically treated geriatric hip fracture patients: a propensity score matching analysis. Reg Anesth Pain Med. Published 17 August 2025. doi:10.1136/rapm-2025-106781

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