Pain medicine

Effectiveness of peri-operative psychological interventions for the reduction of postsurgical pain intensity, depression, anxiety and pain catastrophising: A systematic review and meta-analysis

Eur J AnaesthesiolPublished Systematic review and meta-analysis of randomised trials

Pooled result · Pain intensity after surgeryResult — go to the resultd −0.45 95% CI −0.77 to −0.13

Authors' conclusion

Moderate-quality evidence exists that peri-operative psychological interventions can significantly reduce pain intensity and anxiety postsurgery.

Study context

Population
Adults undergoing any type of surgery27 RCTs
Participants
1,462 vs 1,528
Comparison
Psychological intervention vs Control
  • Psychological interventionn = 1,462
  • Controln = 1,528reference
Outcome
Pain intensity reduction after surgery
Methodological detailsrandom-effects models, moderator analyses
  • Random-effects models
  • Moderator analyses

Pooled result

Pain intensity after surgery

d

−0.45

95% CI −0.77 to −0.13

As reported in the abstract

Further pooled results

Outcomed (95% CI)
Anxiety after surgery−0.33 (−0.54 to −0.11)

Moderator analyses

Interventions delivered by a psychologist more effective than those by other professionals
CBT seemed the most beneficial for surgical patients
Findings in other moderator analyses heterogeneous

Original publication

Effectiveness of peri-operative psychological interventions for the reduction of postsurgical pain intensity, depression, anxiety and pain catastrophising: A systematic review and meta-analysis. Eur J Anaesthesiol. Published 5 March 2025. doi:10.1097/eja.0000000000002157

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