Perioperative medicine & outcomes
The effects of maximizing stroke volume versus maintaining preoperative resting cardiac index on oxygen delivery, oxygen consumption, and microcirculatory tissue perfusion in patients having major abdominal surgery: The exploratory randomized CUSTOM trial
Authors' conclusion
In our trial, both maximizing stroke volume and maintaining preoperative resting cardiac index resulted in higher intraoperative and postoperative oxygen delivery index than routine care in major abdominal surgery patients.
Study context
- Population
- Patients having major abdominal surgery
- Participants
- 76 patients
- Comparison
- Maximizing stroke volume or maintaining preoperative resting cardiac index vs routine care
Methodological detailsexploratory, three-arm
- Exploratory
- Three-arm
Primary result
As reported in the abstract
Oxygen delivery index · End of surgery
Further findings
Oxygen delivery index · 6 h after surgery
Oxygen delivery index · 6 h after surgery
- Higher with stroke volume maximization or preoperative cardiac index maintenance than routine care
Oxygen consumption index and sublingual microvascular flow index
- No important differences among the three groups
Intraoperative average urethral perfusion index
- Slightly higher with stroke volume maximization or preoperative cardiac index maintenance than routine care
Original publication
The effects of maximizing stroke volume versus maintaining preoperative resting cardiac index on oxygen delivery, oxygen consumption, and microcirculatory tissue perfusion in patients having major abdominal surgery: The exploratory randomized CUSTOM trial. J Clin Anesth. Published 25 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →