Perioperative medicine & outcomes
Effects of chronic kidney disease on complications and mortality after fracture surgery
Pooled result · Postoperative complicationsResult — go to the resultOdds ratio 1.67 95% CI 1.54–1.81Authors' conclusion
Compared with patients in the non-CKD group, patients in the CKD group did not significantly differ in the incidence of most postoperative complications after fracture surgery. However, the CKD group had a significantly greater incidence of myocardial infarction and markedly higher postoperative mortality rates at 30 days, 1 year, 2 years, and 10 years.
Study context
- Population
- Patients with fractures undergoing surgery
- Participants
- 1,615,440 patients · 19 studies
- Comparison
- CKD vs non-CKD in patients undergoing fracture surgery
- Outcome
- Postoperative complications and survival
Pooled result
Postoperative complications
Odds ratio
1.67
95% CI 1.54–1.81
P < 0.00001
CKD vs non-CKD
OR 1.67 (95% CI 1.54–1.81); P < 0.00001
As reported in the abstract
Further pooled results
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Mortality · 30 daysI2 = 84% | 2.71 (2.23–3.28) | P < 0.00001 | |
| Mortality · 1 yearI2 = 85% | 3.17 (2.64–3.82) | P < 0.00001 | |
| Mortality · 2 yearsI2 = 8% | 3.06 (2.88–3.25) | P < 0.00001 | |
| Mortality · 10 yearsI2 = 0% | 6.85 (5.84–8.03) | P < 0.00001 | |
| 0.10.31310Odds ratio (log scale) |
Original publication
Effects of chronic kidney disease on complications and mortality after fracture surgery. Perioper Med (Lond). Published 22 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →