Perioperative medicine & outcomes
Effects of intraoperative blood pressure variability on development of postoperative acute kidney injury among Japanese
Authors' conclusion
In a large-scale observational study of Japanese who underwent non-cardiac surgery, intraoperative BP variability, which was defined by ARV and minimum value of systolic BP, was associated with higher risks of postoperative AKI.
Study context
- Population
- Adults (≥ 20 years) undergoing non-cardiac surgery with GA at Fukuoka University Hospital, 2017–2019
- Participants
- 8,504 cases
- Exposure
- Intraoperative systolic blood pressure (BP) variability
- Outcome
- Postoperative AKI (serum creatinine increase >0.3 mg/dL or 1.5 times from preoperation)
- Follow-up
- Within 48 h after surgery
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Postoperative AKI
- Incidence of postoperative acute kidney injury (AKI)
- 184 (2.16%)
- SD and coefficient of variation (CV): association non-significant after adjustment incl. intraoperative hypotension (P for trend)
- P > 0.05
- Average real variability (ARV): remained significantly associated with AKI after adjustment incl. intraoperative hypotension (P for trend)
- P > 0.007
- Lower minimum SBP associated with increased cumulative incidence of AKI after adjustment (P for trend)
- P < 0.001
Observational data: associations, not effects.
Original publication
Effects of intraoperative blood pressure variability on development of postoperative acute kidney injury among Japanese. Perioper Med (Lond). Published 16 February 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →