Haemodynamics, fluids & transfusion
Variation in postinduction hypotension incidence and patient characteristics depending on the definition used: Application of literature-derived definitions to a prospective cohort
Authors' conclusion
Current heterogeneity in postinduction hypotension definitions leads to substantial variations in reported incidence and identifies clinically different patient groups.
Study context
- Population
- Adults undergoing elective non-cardiac surgery under GA, university hospital, the Netherlands, 2019–2023; literature 2013–202492 studies reviewed
- Participants
- 720 adults
- Exposure
- Literature-derived definitions of postinduction hypotension: MAP <65 mmHg vs >30% decrease in MAP from baseline vs SBP <90 mmHg
- Outcome
- Incidence of postinduction hypotension by literature-derived definitions; overlap and differences in patient characteristics among MAP <65 mmHg, >30% MAP decrease from baseline and SBP <90 mmHg
Methodological detailssingle-centre, continuous BP measurement
- Single-centre
- Continuous BP measurement
Main finding
As reported in the abstract
Incidence of postinduction hypotension and overlap between definitions
Unique definitions identified in 92 studies
56
Incidence in the cohort, range depending on the definition used
10 to 89%
Patients classified as hypotensive by only one of the three thresholds
32%
Observational data: associations, not effects.
Further findings
Patient characteristics by threshold
- >30% decrease in MAP: significantly older, more (cardiovascular) comorbidities, higher ASA physical status
- MAP <65 mmHg or SBP <90 mmHg: generally lower baseline and pre-induction BP than non-hypotensive patients
Original publication
Variation in postinduction hypotension incidence and patient characteristics depending on the definition used: Application of literature-derived definitions to a prospective cohort. Eur J Anaesthesiol. Published 4 June 2026. doi:10. 1097/ eja. 0000000000002426
Composed by AI from the published abstract and checked against it. How Briefs are made →