Haemodynamics, fluids & transfusion

Variation in postinduction hypotension incidence and patient characteristics depending on the definition used: Application of literature-derived definitions to a prospective cohort

Eur J AnaesthesiolPublished Systematic literature search combined with a prospective observational cohort study

Authors' conclusion

Current heterogeneity in postinduction hypotension definitions leads to substantial variations in reported incidence and identifies clinically different patient groups.

Study context

Population
Adults undergoing elective non-cardiac surgery under GA, university hospital, the Netherlands, 2019–2023; literature 2013–202492 studies reviewed
Participants
720 adults
Exposure
Literature-derived definitions of postinduction hypotension: MAP <65 mmHg vs >30% decrease in MAP from baseline vs SBP <90 mmHg
Outcome
Incidence of postinduction hypotension by literature-derived definitions; overlap and differences in patient characteristics among MAP <65 mmHg, >30% MAP decrease from baseline and SBP <90 mmHg
Methodological detailssingle-centre, continuous BP measurement
  • Single-centre
  • Continuous BP measurement

Main finding

As reported in the abstract

Incidence of postinduction hypotension and overlap between definitions

Unique definitions identified in 92 studies

56

Incidence in the cohort, range depending on the definition used

10 to 89%

Patients classified as hypotensive by only one of the three thresholds

32%

Observational data: associations, not effects.

Further findings

Patient characteristics by threshold

>30% decrease in MAP: significantly older, more (cardiovascular) comorbidities, higher ASA physical status
MAP <65 mmHg or SBP <90 mmHg: generally lower baseline and pre-induction BP than non-hypotensive patients

Original publication

Variation in postinduction hypotension incidence and patient characteristics depending on the definition used: Application of literature-derived definitions to a prospective cohort. Eur J Anaesthesiol. Published 4 June 2026. doi:10.1097/eja.0000000000002426

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