Respiratory failure & ventilation
Effects of non-invasive respiratory support in post-operative patients: a systematic review and network meta-analysis
Pooled result · Re-intubation rateResult — go to the resultOdds ratio 0.49 95% CI 0.28–0.87Authors' conclusion
In post-operative patients receiving NRS after extubation, NIV reduced the rate of re-intubation, compared to COT, when used for treatment of post-extubation respiratory failure and in patients at high risk of post-extubation respiratory failure.
Study context
- Population
- Adults extubated after surgery
- Participants
- 11,292 adults · 33 studies
- Comparison
- NRS modalities vs conventional oxygen therapy (COT) after extubation
- Outcome
- Re-intubation rate
Methodological detailsSearch of Medline, Embase, Scopus, Cochrane CENTRAL and Web of Science from inception until February 2, 2024
- Search of Medline, Embase, Scopus, Cochrane CENTRAL and Web of Science from inception until February 2, 2024
Pooled result
As reported in the abstract
Odds ratio
0.49
95% CI 0.28–0.87
P = 0.015
NIV vs COT
OR 0.49 (95% CI 0.28–0.87); P = 0.015
Further pooled results
Re-intubation rate by indication and risk (subgroup)
- Non-invasive ventilation (NIV) effect observed for treatment, not prevention, of post-extubation respiratory failure
- NIV effect observed in high-risk, not low-risk, patients
Nosocomial pneumonia, intensive care unit (ICU) LOS, ICU, hospital and long-term mortality
- NIV reduced nosocomial pneumonia, ICU LOS, and ICU, hospital and long-term mortality
Safety
- NIV did not worsen patient discomfort
Original publication
Effects of non-invasive respiratory support in post-operative patients: a systematic review and network meta-analysis. Crit Care. Published 8 May 2024. doi:10.
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