Respiratory failure & ventilation
Effects of out-of-bed armchair positioning on oxygenation in spontaneously breathing intensive care unit (ICU) patients receiving respiratory support: a randomized controlled trial
Authors' conclusion
In spontaneously breathing ICU patients receiving respiratory support, out-of-bed armchair positioning was associated with higher oxygenation after 3 h than remaining in a semi-recumbent position, with no serious adverse events observed.
Study context
- Population
- Spontaneously breathing adult ICU patients receiving invasive pressure support ventilation, HFNO or NIVrandomized
- Participants
- 284 participants
- Comparison
- Out-of-bed armchair vs in-bed semi-recumbent positioning for 3 h
- Armchairn = 146
- Bedn = 138reference
- Primary endpoint
- Change in PaO2/FiO2 (P/F) ratio
- Follow-up
- 3 h
Methodological detailssingle-centre
- Single-centre
Primary result
As reported in the abstract
P/F ratio change
P/F ratio change, Armchair
increased by 13 mm Hg
95% CI 1–24
P/F ratio change, Bed
decreased by 13 mm Hg
95% CI - 25 to - 1
Further findings
Post-positioning marginal mean P/F ratio · 3 h
P = 0.004
Baseline P/F ratio
- Did not differ between groups
Safety
Events
| Outcome | Armchair | Bed |
|---|---|---|
| Serious adverse events | 0 | 0 |
Minor adverse events
- More frequent in the armchair group but minimal impact on positioning duration
Original publication
Effects of out-of-bed armchair positioning on oxygenation in spontaneously breathing ICU patients receiving respiratory support: a randomized controlled trial. Intensive Care Med. Published 18 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →