Perioperative medicine & outcomes
Effects of perioperative tight glycemic control on prognosis in diabetic abdominal surgery patients: a systematic review and meta-analysis
Authors' conclusion
Compared to perioperative CGC, perioperative TGC, which maintains blood glucose levels at 4.44-6.67 mmol/L, can significantly improve the prognosis of patients undergoing abdominal surgery.
Study context
- Population
- Diabetic patients undergoing abdominal surgery
- Participants
- 2,709 patients · 30 studies
- Comparison
- Perioperative tight glycaemic control vs conventional glycaemic control
Pooled result
As reported in the abstract
- Tight glycemic control (TGC) significantly reduced incidence of surgical site infections
- TGC significantly reduced respiratory tract infections
- TGC significantly reduced overall complications (publication bias noted; conclusion unaffected)
- No difference in incidence of urinary tract infections
Further pooled results
Wound healing time and hospital LOS
- Potential reduction with TGC attenuated by publication bias; LOS further confounded by significant heterogeneity
Safety
- TGC significantly reduced incidence of hypoglycemia (heterogeneity noted; conclusion unaffected)
Original publication
Effects of perioperative tight glycemic control on prognosis in diabetic abdominal surgery patients: a systematic review and meta-analysis. Perioper Med (Lond). Published 19 February 2026. doi:10.
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