Perioperative medicine & outcomes
Intraoperative tight blood glucose control reduces the incidence of postoperative pneumonia in minimally invasive esophagectomy: A randomized clinical trial
Primary result · Postoperative pneumoniaResult — go to the resultOdds ratio 0.569 95% CI 0.39–0.83Authors' conclusion
Intraoperative tight blood glucose control is beneficial in reducing the incidence of postoperative pneumonia for minimally invasive esophagectomy patients.
Study context
- Population
- Patients undergoing minimally invasive esophagectomy84 analysed
- Participants
- 88 patients
- Comparison
- Tight vs non-tight intraoperative blood glucose control
- Tight blood glucose controln = 44
- Non-tight blood glucose controln = 44reference
- Primary endpoint
- Incidence of postoperative pneumonia
Methodological detailssingle-blind
- Single-blind
Primary result
Postoperative pneumonia
Odds ratio
0.569
95% CI 0.39–0.83
P = 0.011
Events by treatment group
Tight blood glucose control vs Non-tight blood glucose control
OR 0.569 (95% CI 0.39–0.83); P = 0.011
As reported in the abstract
Secondary outcomes
Demand for advanced antibiotics
P = 0.034
| Outcome | Tight blood glucose control | Non-tight blood glucose control | P value |
|---|---|---|---|
| C-reactive protein · POD 1 | 78.3 (range 30.4–103.7) | 95.6 (range 79.0–130.5) | P = 0.008 |
Original publication
Intraoperative tight blood glucose control reduces the incidence of postoperative pneumonia in minimally invasive esophagectomy: A randomized clinical trial. Anaesth Crit Care Pain Med. Published 15 October 2025. doi:10. 1016/ j. accpm. 2025. 101645
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