Effects on mortality of blood purification techniques in severe septic shock patients. An updated Bayesian network meta-analysis of randomized controlled trials
Authors' conclusion
The PMX filter and HA 330 for blood purification greatly lower mortality rates in patients experiencing severe septic shock.
Study context
- Population
- Patients with severe septic shock
- Participants
- 2,678 patients · 31 randomized clinical trials (RCTs)
- Comparison
- Blood purification techniques vs standard treatment
- Outcome
- Death rate
Methodological detailsfixed effects, SUCRA ranking
- Fixed effects
- SUCRA ranking
Pooled result
As reported in the abstract
Mortality
- PMX and HA 330 the sole devices that notably decreased mortality vs standard treatment (15 treatment approaches)
Further pooled results
- Convection at any prescribed convective dose: greater mortality vs standard therapy
Original publication
Effects on mortality of blood purification techniques in severe septic shock patients. An updated Bayesian network meta-analysis of randomized controlled trials. J Crit Care. Published 14 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →