Airway management

Efficacy and adverse events profile of videolaryngoscopy in critically ill patients: subanalysis of the INTUBE study

Br J AnaesthPublished Secondary analysis of the INTUBE prospective cohort study

Primary result · First-pass intubation successResult — go to the resultOR for first-pass intubation success 1.40 95% CI 1.05–1.87

Authors' conclusion

In critically ill patients, videolaryngoscopy was associated with higher first-pass intubation success rates, despite being used in a population at higher risk of difficult airway management. Videolaryngoscopy was not associated with overall risk of major adverse events.

Study context

Population
Critically ill patients undergoing tracheal intubation, 197 sites in 29 countries, 1 October 2018 to 31 July 2019
Participants
2,916 patients · 197 sites
Comparison
Videolaryngoscopy vs direct laryngoscopy
  • Videolaryngoscopyn = 500
  • Direct laryngoscopyn = 2,416reference
Primary endpoint
First-pass intubation success
Methodological detailsinternational, multicentre
  • International
  • Multicentre

Primary result

As reported in the abstract

OR for first-pass intubation success

1.40

95% CI 1.05–1.87

By group

Videolaryngoscopy vs Direct laryngoscopy
OR for first-pass intubation success 1.40 (95% CI 1.05–1.87)

Further findings

Difficult airway predictors

P < 0.001

Safety

OutcomeOR (95% CI)
Major adverse events1.24 (0.95–1.62)
Cardiovascular events0.78 (0.60–1.02)

Original publication

Efficacy and adverse events profile of videolaryngoscopy in critically ill patients: subanalysis of the INTUBE study. Br J Anaesth. Published 17 May 2023. doi:10.1016/j.bja.2023.04.022

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