Pediatric anesthesia & critical care
Efficacy of Incisional Ropivacaine Infiltration by Presternal Multi-Orifice Catheter for Post-sternotomy Pain Relief in Pediatric Patients Undergoing Cardiac Surgery: A Prospective, Randomized, Controlled Study
Authors' conclusion
LA bolus and infusion through presternal multi-orifice catheter provided effective analgesia postoperatively. However, the bolus was more efficacious in the early phase but equivalent in later periods.
Study context
- Population
- Children undergoing cardiac surgery through midline sternotomy, tertiary referral cardiac center
- Participants
- 200 children
- Comparison
- Presternal multi-orifice catheter 0.375% ropivacaine infusion or intermittent bolus vs no local anaesthetic
- Group An = 65
- Group Bn = 64
- Group Cn = 64reference
- Primary endpoint
- Pain by Modified Objective Pain Score (MOPS)
- Follow-up
- 48 hours postextubation
Methodological detailsprospective, double-blind, single-institution
- Prospective
- Double-blind
- Single-institution
Primary result
As reported in the abstract
Pain (MOPS)
- Group B significantly lower early Modified Objective Pain Score (MOPS) at the first hour
- In the later period mean MOPS lower in group A
Further findings
48-h fentanyl consumption · 48 hours — Group A and Group B vs Group C · significantly lower in groups A and B
P < 0.001
| Outcome | P value |
|---|---|
| ICU LOSGroup A and Group B vs Group C · lower in groups A and B | P < 0.001 |
Hospital LOS
- Comparable across groups
- P = 0.07
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Efficacy of Incisional Ropivacaine Infiltration by Presternal Multi-Orifice Catheter for Post-sternotomy Pain Relief in Pediatric Patients Undergoing Cardiac Surgery: A Prospective, Randomized, Controlled Study. J Cardiothorac Vasc Anesth. Published 10 July 2023. doi:10.
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