Efficacy of pulsed radiofrequency treatment duration to the lumbar dorsal root ganglion in lumbar radicular pain: a double-blind randomized controlled trial
Primary result · Pain intensity (NRS)Result — go to the resultMean difference −1.35Authors' conclusion
A 6 min PRF duration provided the most consistent and statistically significant improvement in pain and function, supporting its use as a clinical standard. The 8 min duration may yield additional subjective and functional benefits in selected patients. PRF was safe and well tolerated across all groups.
Study context
- Population
- Patients with chronic unilateral lumbar radicular pain
- Participants
- 60 patients
- Comparison
- Pulsed radiofrequency (PRF) of the dorsal root ganglion (DRG) for 6 or 8 min vs 4 min
- Primary endpoint
- Pain intensity (NRS)
- Follow-up
- 1 week, 2 weeks, 1 month, 3 months, and 6 months
Methodological detailsdouble-blind
- Double-blind
Primary result
As reported in the abstract
6 months
Mean difference
−1.35
P = 0.031
- All groups: significant improvement in Numeric Rating Scale (NRS) over time
- P < 0.001
Secondary outcomes
Functional disability (ODI)
- All groups: significant improvement in ODI over time
- P < 0.001
- Group C had the lowest ODI scores, not statistically significant in ITT analysis
Patient satisfaction (GPE)
- Group C the only group with significant within-group improvement in GPE over time
Original publication
Efficacy of pulsed radiofrequency treatment duration to the lumbar dorsal root ganglion in lumbar radicular pain: a double-blind randomized controlled trial. Reg Anesth Pain Med. Published 4 September 2025. doi:10.
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