Perioperative medicine & outcomes

Enhanced recovery after liver surgery in cirrhotic patients: a systematic review and meta-analysis

Perioper Med (Lond)Published Systematic review and meta-analysis

Pooled result · Overall complicationsResult — go to the resultOdds ratio 0.43 95% CI 0.31–0.61

Authors' conclusion

In cirrhotic patients, ERAS protocol for liver surgery is safe and decreases post-operative complications and LoS.

Study context

Population
Cirrhotic patients undergoing liver surgery5 articles
Participants
646 patients
Comparison
Enhanced recovery after surgery (ERAS) vs standard care
  • ERASn = 327
  • non-ERASn = 319reference
Outcome
Post-operative complications

Pooled result

Overall complications

Odds ratio

0.43

95% CI 0.31–0.61

P < 0.001

ERAS vs non-ERAS
OR 0.43 (95% CI 0.31–0.61); P < 0.001

As reported in the abstract

Further pooled results

OutcomeMean difference (95% CI)P value
LOSOn average 2 days shorter for ERAS- 2.04 (- 3.19 to - 0.89)P < 0.001

90-day mortality, reoperations, readmissions, liver failure

No difference between groups

Original publication

Enhanced recovery after liver surgery in cirrhotic patients: a systematic review and meta-analysis. Perioper Med (Lond). Published 1 April 2024. doi:10.1186/s13741-024-00375-x

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