Perioperative medicine & outcomes
Evidence on Enhanced Recovery After Surgery Protocols in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis of Postoperative Outcomes
Pooled result · Postoperative morbidityResult — go to the resultRelative risk 0.63 95% CI 0.66–0.55Authors' conclusion
ERAS protocols represent a practical approach to improving surgical outcomes in LMICs, with evidence showing reduced postoperative morbidity and hospital stay, without an increase in readmission or mortality.
Study context
- Population
- Surgical patients in low- and middle-income countries (LMICs), mostly abdominal surgery35 studies (23 trials, 12 observational)
- Participants
- 3,163 vs 3,243
- Comparison
- Enhanced Recovery After Surgery (ERAS) protocols vs routine perioperative care
- ERASn = 3,163
- Routine caren = 3,243reference
- Outcome
- Postoperative morbidity
Methodological details84% of publications from South and Southeast Asia, Risk of bias: Cochrane risk of bias tool and Newcastle-Ottawa scale
- 84% of publications from South and Southeast Asia
- Risk of bias: Cochrane risk of bias tool and Newcastle-Ottawa scale
Pooled result
As reported in the abstract
Relative risk
0.63
95% CI 0.66–0.55
Further pooled results
| Outcome | SMD (95% CI) |
|---|---|
| Postoperative hospital LOSI 2 = 86.7 | −0.68 (−0.47 to −0.90) |
30-day postoperative mortality and readmission
- No significant difference
Original publication
Evidence on Enhanced Recovery After Surgery Protocols in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis of Postoperative Outcomes. Anesth Analg. Published 29 January 2026. doi:10. 1213/ ane. 0000000000007875
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