Perioperative medicine & outcomes
Interventions to reduce postoperative mortality in low- and middle-income countries: systematic review
Authors' conclusion
Few RCTs have targeted postoperative mortality in LMICs and no intervention demonstrated consistent effectiveness across multiple contexts.
Study context
- Population
- Surgical patients in LMIC (elective and emergency operations, all surgical specialties)
- Participants
- 95,521 patients · 18 trials
- Outcome
- Postoperative mortality
- Follow-up
- Within 90 days of surgery
Methodological detailspreregistered protocol
- Preregistered protocol
Pooled result
As reported in the abstract
Trials showing a significant reduction in mortality (interventions largely context specific)
4
Trials assessed as low risk of bias
4 of 18
Further pooled results
- Adherence, simple interventions
- 93.6%
- Adherence, complex interventions
- 96.8%
- Generally high and similar; varied substantially across trials
Original publication
Interventions to reduce postoperative mortality in low- and middle-income countries: systematic review. Br J Surg. Published 18 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →