Perioperative medicine & outcomes

Enhanced Recovery After Surgery Guidelines and Hospital Length of Stay, Readmission, Complications, and Mortality: A Meta-Analysis of Randomized Clinical Trials

JAMA Netw OpenPublished Systematic review and meta-analysis of randomised trials

An erratum to this article was published (JAMA Netw Open, 1 Jul 2024 ↗)

Authors' conclusion

In this meta-analysis, ERAS guidelines were associated with decreased hospital length of stay and complications.

Study context

Population
Patients undergoing surgery (9 enhanced recovery after surgery (ERAS)-guided surgical procedures, 21 countries)
Participants
9,076 patients · 74 RCTs
Comparison
ERAS-guided surgery vs usual surgical care
Outcome
Hospital LOS, hospital readmission within 30 days of index discharge, 30-day postoperative complications, and 30-day postoperative mortality
Methodological detailsrandom-effects meta-analysis, meta-regression, 15 (20.3%) studies at low risk of bias, Mean (SD) RECOvER checklist score 13.5 (2.3)
  • Random-effects meta-analysis
  • Meta-regression
  • 15 (20.3%) studies at low risk of bias
  • Mean (SD) RECOvER checklist score 13.5 (2.3)

Pooled result

As reported in the abstract

ERAS vs Usual surgical careRelative risk (complications) (95% CI)P value
I2 = 78.6%
0.71(0.59–0.87)
P < 0.001
I2 = 86.5%
decrease in hospital LOS 1.88 days (95% CI 0.95–2.81); P < 0.001

Original publication

Enhanced Recovery After Surgery Guidelines and Hospital Length of Stay, Readmission, Complications, and Mortality: A Meta-Analysis of Randomized Clinical Trials. JAMA Netw Open. Published 3 June 2024. doi:10.1001/jamanetworkopen.2024.17310

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