Environmental impact of intravenous versus oral administration materials for acetaminophen and ketoprofen in a French university hospital: an eco-audit study using a life cycle analysis
Authors' conclusion
This eco-audit indicates that oral administration of acetaminophen and ketoprofen results in significantly lower carbon emissions and water consumption than intravenous administration.
Study context
- Population
- Perioperative multimodal analgesia with acetaminophen and ketoprofen, French university hospital
- Comparison
- Oral vs IV administration of 1 g acetaminophen and 50 mg ketoprofen
- Outcome
- Greenhouse gas emissions and depletion of water resources
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Greenhouse gas emissions (CO2e)
Intravenous
444-556
g CO2 equivalent (CO2e)
Oral
8.36
g CO2e
Further findings
| Outcome | Intravenous | Oral |
|---|---|---|
| Water waste/consumption | 9.8-12.2 L | 1.16 L |
National-level switch from IV to oral premedication, per year (extrapolation) · each year
- Avoided CO2e emissions
- 2,900-3,700 tons
- Avoided water waste
- 58,000-74,000 m3
Original publication
Environmental impact of intravenous versus oral administration materials for acetaminophen and ketoprofen in a French university hospital: an eco-audit study using a life cycle analysis. Can J Anaesth. Published 10 October 2024. doi:10. 1007/ s12630-024-02852-9
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