Epidemiology, patterns of care and prognosis of acute kidney injury in critically ill patients: A multicenter study in Argentina (The EPIRA study)
Authors' conclusion
ICU-acquired AKI has high incidence, complications and mortality. Risk factors for AKI and RRT utilization were similar to those described in other epidemiological studies. AKIadm was more frequent than AKIhosp, but had equal prognosis.
Study context
- Population
- Critically ill patients in 35 intensive care unit (ICUs) in Argentina, 6 months in 2018
- Participants
- 1,466 patients · 35 ICUs
- Exposure
- Acute kidney injury (AKI) vs non-AKI; AKI on admission vs AKI developed during hospitalization
- AKIn = 900
- Outcome
- Epidemiology (incidence), prognosis and treatment of AKI
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
AKI incidence
Observational data: associations, not effects.
Further findings
| Outcome | AKI | non-AKI | AKIadm | AKIhosp | P value |
|---|---|---|---|---|---|
| Hospital mortality, AKI vs non-AKI | 38.7% | 23.3% | — not stated in the abstract | — not stated in the abstract | P < 0.001 |
| Hospital mortality, AKIadm vs AKIhosp | — not stated in the abstract | — not stated in the abstract | 41.2% | 37.8% | P = 0.53 |
— not stated in the abstract
- Renal replacement therapies (RRT) requirement in AKI patients
- 14.8%
Original publication
Epidemiology, patterns of care and prognosis of acute kidney injury in critically ill patients: A multicenter study in Argentina (The EPIRA study). J Crit Care. Published 27 July 2023. doi:10.
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