Erector spinae plane block versus paravertebral block for major oncological breast surgery: a multicentre randomised controlled trial
Authors' conclusion
Compared with thoracic paravertebral block, erector spinae plane block did not meet the noninferiority criteria and was less effective for complete analgesia.
Study context
- Population
- Women undergoing major breast cancer surgery
- Participants
- 292 women
- Comparison
- Erector spinae plane block (ESPB) vs paravertebral block (PVB)
- Primary endpoint
- Percentage of participants requiring morphine
- Follow-up
- First 2 h after surgery
Methodological detailsprospective, multicentre, double-blind, non-inferiority
- Prospective
- Multicentre
- Double-blind
- Non-inferiority
Primary result
As reported in the abstract
Secondary outcomes
Required dermatomal area not covered
Morphine consumption
- Similar between the groups
Pain scores
- Greater in the ESPB group, especially during mobilisation
Participant satisfaction
- Similar between groups, high in both
Safety
- No major complications observed
Original publication
Erector spinae plane block versus paravertebral block for major oncological breast surgery: a multicentre randomised controlled trial. Br J Anaesth. Published 24 July 2025. doi:10.
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