Respiratory failure & ventilation
Esophageal pressures in supine and prone position: evaluation using high-resolution manometry
Authors' conclusion
A large variation in PES is seen in both supine and prone position but depends on which sensors are included in calculations of PES. There are significant differences in absolute pressures and in influence from mediastinal organs between supine and prone position.
Study context
- Population
- Mechanically ventilated patients before start of spinal surgery
- Participants
- 20 participants
- Comparison
- Prone vs supine position, at PEEP 5 and 12 cmH2O
- Outcome
- Mean end-expiratory (PESEE) and tidal variation of esophageal pressures (ΔPES), measured by high-resolution manometry
Methodological detailscrossover of body position and PEEP
- Crossover of body position and PEEP
Main finding
As reported in the abstract
MD
3.2-5.7
PESEE significantly lower in prone
MD
0.8-1.6 cmH2O
ΔPES significantly higher in prone
Further findings
Mean within-patient variability of PESEE and ΔPES
- Depending on PEEP level and body position
- 38-540%
End-expiratory pressure (PES) from theoretically optimal sensors (PESOPT)
- Lower than mean PESEE from larger esophageal regions and less variable
Original publication
Esophageal pressures in supine and prone position: evaluation using high-resolution manometry. J Clin Monit Comput. Published 11 June 2026. doi:10.
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