Evaluating the effectiveness of bilateral erector spinae plane blocks in addition to standard multimodal analgesia at reducing opioid consumption in patients undergoing elective mammoplasty in an ambulatory surgical center: a randomized clinical trial
Authors' conclusion
An ESP block prior to breast reduction mammoplasty did not translate to a clinically meaningful reduction in opioid usage in the immediate postoperative period.
Study context
- Population
- Patients undergoing elective breast reduction mammoplastyrandomized
- Participants
- 78 patients
- Comparison
- Block vs No-block
- Primary endpoint
- Cumulative oral MME consumption
- Follow-up
- 24 hours postsurgery
Methodological detailsambulatory surgical center
- Ambulatory surgical center
Primary result
As reported in the abstract
Cumulative oral MME
Block
10.6
mean
No-block
17.5
mean
P = 0.014
Further findings
Time to discharge after PACU admission
P = 0.012
Any opioid use during PACU stay
P = 0.006
Pain at discharge, 24-hour pain scores, overall anesthesia satisfaction
- Not significantly different between the groups
Safety
Nausea and vomiting in post-anesthesia care unit (PACU)
- Not significantly different between the groups
Original publication
Evaluating the effectiveness of bilateral erector spinae plane blocks in addition to standard multimodal analgesia at reducing opioid consumption in patients undergoing elective mammoplasty in an ambulatory surgical center: a randomized clinical trial. Reg Anesth Pain Med. Published 9 July 2026. doi:10.
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