Cardiac arrest & resuscitation

Evaluating the impact of Extracorporeal Life Support Organization (ELSO) guideline adherence on favorable neurological outcomes among patients requiring extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest

ResuscitationPublished Post-hoc analysis of a multicentre prospective study

Authors' conclusion

Patients who adhered more closely to specific inclusion criteria of the ELSO guidelines demonstrated a tendency towards a higher rate of favorable neurological outcomes. However, the relationship was heterogeneous according to initial rhythm.

Study context

Population
Adults with out-of-hospital cardiac arrest (OHCA) treated with extracorporeal cardiopulmonary resuscitation (ECPR), 2019–2021of 9,909 patients
Participants
227 adults
Comparison
Number of ELSO criteria met
  • 0 pointsn = 3reference
  • 1 pointn = 23
  • 2 pointsn = 67
  • 3 pointsn = 82
  • 4 pointsn = 43
Primary endpoint
Favorable neurological outcome (Cerebral Performance Category 1 or 2)
Follow-up
30 days

Primary result

As reported in the abstract

Favorable neurological outcome by number of ELSO criteria met

Further findings

Favorable neurological outcome, initial shockable rhythm (subgroup)

Similar tendency observed

Favorable neurological outcome, initial non-shockable rhythm (subgroup)

No such relationship observed

Original publication

Evaluating the impact of ELSO guideline adherence on favorable neurological outcomes among patients requiring extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest. Resuscitation. Published 20 April 2024. doi:10.1016/j.resuscitation.2024.110218

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