Pediatric anesthesia & critical care
Evaluating the role for regional analgesia in children with spina bifida: a retrospective observational study comparing the efficacy of regional versus systemic analgesia protocols following major urological surgery
Authors' conclusion
Continuous regional analgesia following major urological surgery in children with spina bifida was associated with a 70% intraoperative and 78% postoperative reduction in opioids without higher pain scores.
Study context
- Population
- Children with spina bifida undergoing bladder augmentation or creation of catheterizable channels, 2009–2021; epidural analgesia excluded
- Participants
- 158 children · 7 centres
- Exposure
- Peripheral regional catheters vs no regional analgesia
- Regional cathetersn = 87
- No regionaln = 71reference
- Outcome
- Postoperative opioid use (morphine equivalents normalised to weight)
Methodological detailsmulticentre database
- Multicentre database
Main finding
As reported in the abstract
In-hospital postoperative opioid usage
P < 0.01
Observational data: associations, not effects.
Further findings
Intraoperative opioid usage
P < 0.01
Anesthesia setup time
P < 0.01
Pain scores
- Pain scores not higher in the regional catheters group
Original publication
Evaluating the role for regional analgesia in children with spina bifida: a retrospective observational study comparing the efficacy of regional versus systemic analgesia protocols following major urological surgery. Reg Anesth Pain Med. Published 27 September 2022. doi:10.
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