Cardiac arrest & resuscitation
Evaluating the effect of a regional training initiative on bystander cardiopulmonary resuscitation rates after out-of-hospital cardiac arrest
Main finding · Bystander CPR rate, overallResult — go to the resultAdjusted intervention effect 2.94 percentage-points 95% CI −0.95 to 6.83Authors' conclusion
While we observed an increasing trend in bystander CPR rates in all regions, this change was not associated with the intervention. However, we found that the intervention was associated with a significant increase in bystander CPR rates for public OHCAs.
Study context
- Population
- Out-of-hospital cardiac arrest (OHCA) events (excluding health care facilities), Cardiac Arrest Registry to Enhance Survival (CARES) registry, January 2022 to December 2024
- Participants
- 20,414 events
- Exposure
- Intervention region vs Control counties
- Intervention regionn = 15,417
- Outcome
- Change in bystander CPR rates associated with the intervention, stratified by home and public locations
Methodological detailsdifference-in-differences, CARES registry
- Difference-in-differences
- CARES registry
Main finding
Bystander CPR rate, overall
Adjusted intervention effect
2.94 percentage-points
95% CI −0.95 to 6.83
As reported in the abstract
- Bystander cardiopulmonary resuscitation (CPR) rate in intervention region, pre- to post-intervention
- 37.4% to 42.5%
Observational data: associations, not effects.
Secondary outcomes
Bystander CPR rates, public locations (subgroup)
| Percentage-point increase (95% CI) | ||
|---|---|---|
| InterventionSignificant; adjusted model · adjusted model | 8.59 (0.22–16.96) | |
| −1001020Difference (linear scale) |
Bystander CPR rates, home locations (subgroup)
- No significant intervention effect in home locations
Survival to hospital discharge and neurologically intact survival
- No significant intervention effect between pre- and post-intervention periods
Original publication
Evaluating the effect of a regional training initiative on bystander cardiopulmonary resuscitation rates after out-of-hospital cardiac arrest. Resuscitation. Published 15 August 2026. doi:10.
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