Pediatric anesthesia & critical care
Evaluation of propofol‐based procedural sedation in pediatric hemato‐oncological patients provided by physician assistants in anesthesia
Authors' conclusion
Sedation and analgesia for short painful procedures in selected pediatric hemato-oncological units with a dedicated protocol may be safely provided by trained and certified Physician Assistants in Anesthesia.
Study context
- Population
- Pediatric patients meeting criteria for deep sedation by Physician Assistants in Anesthesia, scheduled for a hemato-oncological procedure (e.g. lumbar and bone marrow punctures), Amalia Children's Hospital, Radboudumc Nijmegen437 sedation sessions
- Participants
- 71 patients
- Outcome
- Oxygen desaturation below 92% for more than 20 s
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Oxygen desaturation <92% for >20 s
- Oxygen desaturation below 92% lasting longer than 20 s
- 0
Observational data: associations, not effects.
Further findings
Airway interventions
- Jaw thrust
- 2
- Invasive airway techniques (oropharyngeal cannula, laryngeal mask, or intubation)
- 0
Safety
Airway interventions
- Jaw thrust performed
- 2
- Invasive airway techniques (oropharyngeal cannula, LMA or intubation)
- 0
Significant drop in MAP
- Cases with significant drop in MAP
- 2 out of 437 cases (0.5%)
CPR, aspiration, laryngeal spasm
- No CPR or other adverse events such as aspiration or laryngeal spasm
Original publication
Evaluation of propofol‐based procedural sedation in pediatric hemato‐oncological patients provided by physician assistants in anesthesia. Paediatr Anaesth. Published 3 October 2024. doi:10.
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