Pediatric anesthesia & critical care
Extracorporeal cardiopulmonary resuscitation for pediatric out-of-hospital cardiac arrest: A review of the Extracorporeal Life Support Organization Registry
Authors' conclusion
These preliminary data suggest that while overall survival is poor, a carefully selected pediatric OHCA patient may benefit from ECPR.
Study context
- Population
- Children 28 days to 18 years old who received extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA), ELSO Registry, January 2020 to May 2023
- Participants
- 80 children
- Outcome
- Survival to hospital discharge
Methodological detailsExtracorporeal Life Support Organization Registry
- Extracorporeal Life Support Organization Registry
Main finding
As reported in the abstract
Survival to discharge
29.9%
Observational data: associations, not effects.
Further findings
Predictors of survival (unadjusted)
| Unadjusted OR (CI) | P value | ||
|---|---|---|---|
| Initial shockable rhythmIncreased odds of survival | 4.7 (1.5–14.5) | P = 0.006 | |
| Signs of life prior to ECMOIncreased odds of survival | 7.8 (2.6–23.4) | P < 0.001 | |
| Lactate early on-ECMODecreased odds of survival | 0.89 (0.79–0.99) | P = 0.02 | |
| Lactate at 24 h on-ECMODecreased odds of survival | 0.62 (0.42–0.91) | P < 0.001 | |
| 0.050.21520Unadjusted odds ratio (log scale) |
Patient and arrest characteristics
- Median age
- 8.8 years [2.0-15.8]
- Male
- 53.8%
- Witnessed OHCA
- 65.0%
- Bystander cardiopulmonary resuscitation (CPR)
- 46.3%
- Initial shockable rhythm
- 26.3%
- Total CPR duration
- 78 min [52-106]
- Signs of life
- 31.3%
- Cardiac etiology precipitating event
- 45.0%
Original publication
Extracorporeal cardiopulmonary resuscitation for pediatric out-of-hospital cardiac arrest: A review of the Extracorporeal Life Support Organization Registry. Resuscitation. Published 1 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →