Trauma & major bleeding

Extracorporeal membrane oxygenation in trauma patient in France: A retrospective nationwide registry

Anaesth Crit Care Pain MedPublished Retrospective cohort study

Authors' conclusion

In-hospital mortality of trauma patients requiring ECMO for refractory ARDS varied according to indications. The best prognosis was observed in the subgroup of pneumonia-induced ARDS patients.

Study context

Population
Patients admitted for major trauma receiving Veno-venous (VV) or veno-arterial (VA) extracorporeal membrane oxygenation (ECMO), 17 Level 1 trauma centres in France, January 2010–December 202152,851 screened
Participants
179 patients
Exposure
VV ECMO vs VA ECMO
  • VV ECMOn = 143
  • VA ECMOn = 36
Outcome
In-hospital mortality
Methodological detailsobservational, multicentre, nationwide registry
  • Observational
  • Multicentre
  • Nationwide registry

Main finding

As reported in the abstract

Observational data: associations, not effects.

Further findings

In-hospital deaths by ECMO indication (VV ECMO subgroup)

Deaths after cannulation for chest injuries
33 (48.5%)
Deaths after cannulation for ventilator-associated pneumonia (VAP)
22 (39.3%)
Deaths after cannulation for extrapulmonary acute respiratory distress syndrome (ARDS)
10 (55.6%)

Indications for VV ECMO

Chest injuries
n = 68, 47.6%
VAP
n = 57, 39.9%
Extra-respiratory ARDS
n = 57, 39.9%

Original publication

Extracorporeal membrane oxygenation in trauma patient in France: A retrospective nationwide registry. Anaesth Crit Care Pain Med. Published 20 December 2024. doi:10.1016/j.accpm.2024.101457

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