Cardiac arrest & resuscitation
Factors associated with circulatory death after out-of-hospital cardiac arrest: a population-based cluster analysis
Main finding · RPRSResult — go to the resultHazard ratio 5.51 95% CI 4.51–6.74Authors' conclusion
We identified patient clusters based on Utstein criteria, and one cluster was strongly associated with RPRS.
Study context
- Population
- Adults admitted alive to intensive care unit (ICUs) after out-of-hospital cardiac arrest (OHCA) in 2011–2018, Paris region (France) registry
- Participants
- 4,445 adults
- Exposure
- Patient clusters based on Utstein clinical and laboratory variables
- Outcome
- Death from refractory postresuscitation shock (RPRS) in each cluster
Methodological detailspopulation-based, unsupervised hierarchical cluster analysis, prospective registry
- Population-based
- Unsupervised hierarchical cluster analysis
- Prospective registry
Main finding
RPRS
Hazard ratio
5.51
95% CI 4.51–6.74
Cluster 4
HR 5.51 (95% CI 4.51–6.74)
As reported in the abstract
Observational data: associations, not effects.
Further findings
ICU outcome (all patients)
- Discharged alive from the ICU
- 1468 (33%)
- Died in the ICU
- 2977 (67%)
Original publication
Factors associated with circulatory death after out-of-hospital cardiac arrest: a population-based cluster analysis. Ann Intensive Care. Published 9 June 2023. doi:10.
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