Cardiac arrest & resuscitation
Factors associated with fever after cardiac arrest: A post‐hoc analysis of the FINNRESUSCI study
Primary result · Favourable functional outcome at 12 monthsResult — go to the resultOdds ratio 0.90 95% CI 0.44–1.84Authors' conclusion
Half of OHCA patients not treated with TTM developed fever. We found no association between fever and outcome.
Study context
- Population
- Intensive care unit (ICU)-treated out-of-hospital cardiac arrest (OHCA) patients not treated with TTM, five Finnish university hospitals and 14 central hospitals, 2010–201112-month cerebral performance category (CPC) missing in 7
- Participants
- 192 participants
- Comparison
- Fever vs no fever
- Fevern = 89
- Primary endpoint
- Favourable functional outcome (CPC 1 or 2)
- Follow-up
- 12 months
Methodological detailsmulticentre, binary logistic regression
- Multicentre
- Binary logistic regression
Primary result
Favourable functional outcome at 12 months
Odds ratio
0.90
95% CI 0.44–1.84
Fever vs No fever
OR 0.90 (95% CI 0.44–1.84)
As reported in the abstract
- Patients with favourable functional outcome at 12 months
- 51 (28%)
Further findings
ROSC delay
P < 0.01
| Outcome | OR (95% CI) | |
|---|---|---|
| Predictor of fever within 72 h: initial non-shockable rhythmNon-shockable initial rhythm vs Shockable initial rhythm · only factor associated with increased risk of fever | 2.99 (1.51–5.94) | |
| 0.20.5125Odds ratio (log scale) |
- Incidence of fever within 72 h of ICU admission
- 46% · 89
Fever within 72 h by initial rhythm (shockable vs non-shockable)
- Incidence of fever, shockable vs non-shockable initial rhythm
- 28% vs. 72%, p < .01
Time and area over temperature thresholds (37°C to 40°C) within 24, 48 or 72 h
- Not significantly different between favourable and unfavourable functional outcome
Original publication
Factors associated with fever after cardiac arrest: A post‐hoc analysis of the FINNRESUSCI study. Acta Anaesthesiol Scand. Published 13 February 2024. doi:10.
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