Pain medicine

Factors associated with poor pain experience after surgery

Reg Anesth Pain MedPublished Secondary analysis (exploratory) of a multicentre cohort

Primary result · Poor pain experienceResult — go to the resultOdds ratio 26.96 95% CI 2.17–334.23

Authors' conclusion

The intraoperative use of remifentanil and sufentanil is independently associated with poorer postoperative pain experience.

Study context

Population
Adults undergoing elective surgery under GA, five French teaching hospitals
Participants
971 adults · 5 hospitals
Comparison
Patient-related and procedural factors associated with poor postoperative pain experience
Primary endpoint
Patient experience by EVAN-G questionnaire; poor pain experience = score below 25th percentile on EVAN-G pain dimension
Follow-up
POD 1
Methodological detailsunivariate and multivariate logistic regression
  • Univariate and multivariate logistic regression

Primary result

Poor pain experience

Odds ratio

26.96

95% CI 2.17–334.23

P = 0.01

Intraoperative remifentanil and sufentanil
OR 26.96 (95% CI 2.17–334.23); P = 0.01

As reported in the abstract

Poor pain experience reported
271 (27.9%)

Further findings

Other factors associated with poor pain experience (multivariate)

ORP value
AgeLower likelihood0.97P = 0.003
Absence of premedicationLower likelihood0.49P = 0.035
Orthopedic surgeryLower likelihood0.29P = 0.005
ASA 3 statusPredictor5.09P = 0.028
Postoperative anxiolytic usePredictor8.20P < 0.001
AmnesiaPredictor1.58P = 0.001
OutcomeP value
Other factors associated with poor pain experience (multivariate)Higher VAS pain on day 1 · predictorP < 0.001
Other factors associated with poor pain experience (multivariate)Lower well-being scores on day 1 · predictorP = 0.007

Original publication

Factors associated with poor pain experience after surgery. Reg Anesth Pain Med. Published 25 February 2025. doi:10.1136/rapm-2024-106095

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