Hypnosis for unplanned procedural pain in the intensive care unit: the HYPIC randomized clinical trial
Primary resultResult — go to the resultDifference 0 pts 95% CI −1.3 to 1.3Authors' conclusion
While hypnosis did not result in a statistically significant reduction in unplanned procedural pain, it seems to reduce anxiety, increase comfort, and reduce the stress level of healthcare providers.
Study context
- Population
- Critically ill patients undergoing an unplanned invasive procedure in two French intensive care units (ICUs), 2019–2022
- Participants
- 78 patients
- Comparison
- Hypnosis vs Standard care
- Primary endpoint
- Pain level during the invasive procedure (numeric pain scale, 0-10)
- Follow-up
- Immediately after the end of the procedure
Methodological detailssingle-blind, multicentre
- Single-blind
- Multicentre
Primary result
As reported in the abstract
Difference
0 pts
95% CI −1.3 to 1.3
P = 0.89
By group
Hypnosis
2.2
± 2.9
Standard care
2.2
± 3
Hypnosis vs Standard care
difference 0 pts (95% CI −1.3 to 1.3); P = 0.89
Secondary outcomes
| Outcome | Hypnosis | Standard care | Difference (CI) | P value | |
|---|---|---|---|---|---|
| Anxiety level | 2.4 ± 2.8 | 4.1 ± 3 | - 1.7 (−3 to −0.4) | P = 0.01 | |
| Stress experienced by ICU nurses | 0.1 ± 0.4 | 0.9 ± 1.5 | - 0.8 (−1.3 to −0.3) | P = 0.003 | |
| −4−202Difference (linear scale) |
| Outcome | OR (CI) | P value | |
|---|---|---|---|
| Need for increased lidocaine consumption | 0.3 (0.13–0.84) | P = 0.02 | |
| 0.10.31310Odds ratio (log scale) |
Original publication
Hypnosis for unplanned procedural pain in the intensive care unit: the HYPIC randomized clinical trial. Crit Care. Published 18 July 2025. doi:10.
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