Perioperative medicine & outcomes

The feasibility of implementing and evaluating individualised digital prehabilitation prior to major elective surgery in adults aged ≥ 50 years: the PreActiv intervention

Perioper Med (Lond)Published Single-arm feasibility study

Authors' conclusion

A definitive study investigating the effects of this novel digital prehabilitation programme on postoperative outcomes is feasible based on achieving predefined progression criteria, and warranted based on high compliance and acceptability.

Study context

Population
Patients aged ≥ 50 years awaiting major elective surgery in ≥ 10 weeks
Participants
35 patients
Outcome
Retention (completing follow-up measurements) and adherence (completing all exercise sessions), assessed against Stop criteria ≤ 50%
Methodological detailsprospectively registered
  • Prospectively registered

Main finding

As reported in the abstract

Retention (completing follow-up measurements) and adherence (completing all exercise sessions); Stop criteria ≤ 50%

Retention rate

69%

Exercise adherence in study completers

88%

Secondary outcomes

Compliance (correct exercise intensity, type and duration)

Sessions completed with correct intensity, type and duration
79%

Acceptability

All participants reported exercise videos easy to follow and would recommend the programme
Concern when completion of prehabilitation did not coincide with surgery date
In-person measurement visits a barrier to recruitment and retention

Signal of effect (pre- to post-intervention)

Functional fitness, quality of life and mood improved
Cardiorespiratory fitness unchanged at group level, with individual clinically-meaningful improvements

Safety

No related serious adverse events

Original publication

The feasibility of implementing and evaluating individualised digital prehabilitation prior to major elective surgery in adults aged ≥ 50 years: the PreActiv intervention. Perioper Med (Lond). Published 3 March 2026. doi:10.1186/s13741-026-00663-8

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