Perioperative medicine & outcomes
Preoperative Exercise to Improve Fitness in Patients Undergoing Complex Surgery for Cancer of the Lung or Esophagus (PRE-HIIT)): A Randomized Controlled Trial
Primary result · VO 2 peak, pre- to post-interventionResult — go to the resultBetween-group difference 6.6 %Authors' conclusion
HIIT is effective for eliciting meaningful gains in preoperative fitness in a deconditioned cohort within short timeframes.
Study context
- Population
- Patients scheduled for curative resection for lung or esophageal cancer with ≥2-weeks preoperative lead-in
- Participants
- 79 patients
- Comparison
- High-intensity interval training (HIIT) vs standard care
- HIITn = 41
- Standard care (SC)n = 38reference
- Primary endpoint
- VO 2 peak, measured by cardiopulmonary exercise testing
Methodological detailsparallel, 2-armed
- Parallel
- 2-armed
Primary result
VO 2 peak, pre- to post-intervention
Between-group difference
6.6 %
P = 0.05
By group
As reported in the abstract
Secondary outcomes
Sit-to-stand scores
- Significantly improved with HIIT
- P = 0.02
Original publication
Preoperative Exercise to Improve Fitness in Patients Undergoing Complex Surgery for Cancer of the Lung or Esophagus (PRE-HIIT)): A Randomized Controlled Trial. Ann Surg. Published 6 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →