Fetal outcomes with and without the use of sugammadex in pregnant patients undergoing non-obstetric surgery: a multicenter retrospective study
Authors' conclusion
Having GA with SGX or GA without SGX did not result in different rates of miscarriage or preterm birth within four weeks after the procedure.
Study context
- Population
- Pregnant women undergoing non-obstetric surgery at three tertiary perinatal care centres in Japan, January 2013 to December 2020
- Participants
- 124 women
- Exposure
- GA with sugammadex vs GA without sugammadex
- GA with SGXn = 73
- GA without SGXn = 51reference
- Outcome
- Miscarriage or preterm birth
- Follow-up
- Within four weeks after surgery
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Odds ratio
1.42
95 % CI 0.19–10.47
P = 1.00
By group
GA with SGX vs GA without SGX
OR 1.42 (95 % CI 0.19–10.47); P = 1.00
Observational data: associations, not effects.
Original publication
Fetal outcomes with and without the use of sugammadex in pregnant patients undergoing non-obstetric surgery: a multicenter retrospective study. Int J Obstet Anesth. Published 23 December 2022. doi:10. 1016/ j. ijoa. 2022. 103620
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