ICU sedation, delirium & recovery
Five-year mortality and functional trajectories in older survivors of intensive care compared to the general population
Authors' conclusion
Amongst adults aged 60-89 years, the impact of critical illnesses is still detectable 5 years after surviving intensive care.
Study context
- Population
- Individuals aged 60–99 years, members of a statutory health insurance organisation in Germany
- Participants
- 3,261,169 individuals
- Exposure
- Older ICU survivors vs the general population
- Survivorsn = 40,441
- Outcome
- Survival and functional trajectories
- Follow-up
- 5 years
Methodological detailsclaims data, multi-state modelling
- Claims data
- Multi-state modelling
Main finding
As reported in the abstract
- Excess mortality after ICU peaked in previously fit survivors aged 60-79 years, who also had higher risk of functional decline vs peers in the general population
- Advanced age attenuated differences, which disappeared amongst nonagenarians
Observational data: associations, not effects.
Further findings
Transition from no functional deficit to mild-moderate deficits, by sex
- Women at higher risk than men
Original publication
Five-year mortality and functional trajectories in older survivors of intensive care compared to the general population. Intensive Care Med. Published 17 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →