Cardiac arrest & resuscitation
Fluid balance and outcome in cardiac arrest patients admitted to intensive care unit
Authors' conclusion
After cardiac arrest, a positive fluid balance is consistently associated with a worse outcome.
Study context
- Population
- Adult out-of-hospital cardiac arrest (OHCA) patients admitted to 17 ICUs, August 2020 to June 202274% positive fluid balance
- Participants
- 816 patients
- Exposure
- Positive vs non-positive fluid balance
- Outcome
- Survival
- Follow-up
- 90 days
Methodological detailsconsecutive enrolment, multivariate Cox analysis, propensity-score matched, landmark analysis, sensitivity analyses
- Consecutive enrolment
- Multivariate Cox analysis
- Propensity-score matched
- Landmark analysis
- Sensitivity analyses
Main finding
As reported in the abstract
90-day survival; mortality
Positive fluid balance vs Non-positive fluid balanceHazard ratio (mortality) (CI)P value
Adjusted multivariate analysis
1.8(1.3–2.3)
P < 0.001Propensity score matching, n = 193 matched pairs
1.6(1.1–2.1)
P = 0.005- Alive at 90 days, all patients
- 291 of 816 (36%)
Observational data: associations, not effects.
Further findings
Need for RRT
P = 0.001
| Outcome | Positive fluid balance | Non-positive fluid balance | P value |
|---|---|---|---|
| Minimum PaO2/FiO2 ratio · first seven days | 158 | 180 | P < 0.001 |
Original publication
Fluid balance and outcome in cardiac arrest patients admitted to intensive care unit. Crit Care. Published 14 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →