Cardiac arrest & resuscitation
Prospective comparison of prognostic scores for prediction of outcome after out-of-hospital cardiac arrest: results of the AfterROSC1 multicentric study
Authors' conclusion
In patients admitted to ICUs after a successfully resuscitated OHCA, most of the scores available for the evaluation of the subsequent prognosis are more efficient than the usual Utstein criteria but calibration is unacceptable for some of them.
Study context
- Population
- Comatose (GCS ≤ 8) patients with non-traumatic out-of-hospital cardiac arrest (OHCA) and stable return of spontaneous circulation (ROSC) admitted to 24 French and Belgian Intensive Care Units (ICUs), August 2020–June 2022907 screened
- Participants
- 658 participants
- Comparison
- Dedicated prognostic scores vs Utstein style criteria
- Outcome
- Modified Rankin scale (mRS) assessed by phone interview
- Follow-up
- Day 90 after cardiac arrest
Performance
As reported in the abstract
Poor outcome prediction (AUROC) · day 90
| Test or model | Value | AUROC | AUROC range |
|---|---|---|---|
| Utstein criteria | 0.79 (CI 0.76–0.83) | 0.79 | |
| Other scores | 0.79 [0.75-0.83] to 0.88 [0.86-0.91] | 0.79 [0.75-0.83] to 0.88 [0.86-0.91] |
Value
Utstein criteria0.79 (CI 0.76–0.83)
Other scores0.79 [0.75-0.83] to 0.88 [0.86-0.91]
AUROC
Utstein criteria0.79
Other scores— not stated in the abstract
AUROC range
Utstein criteria— not stated in the abstract
Other scores0.79 [0.75-0.83] to 0.88 [0.86-0.91]
Further findings
Mortality and unfavorable neurological outcome · day 90
- Mortality rate
- 63%
- Unfavorable neurological outcomes
- 66%
Proportion of patients for whom score could not be calculated
- Range across scores
- 1.4% to 17.4%
Original publication
Prospective comparison of prognostic scores for prediction of outcome after out-of-hospital cardiac arrest: results of the AfterROSC1 multicentric study. Ann Intensive Care. Published 11 October 2023. doi:10. 1186/ s13613-023-01195-w
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