Cardiac arrest & resuscitation

Prospective comparison of prognostic scores for prediction of outcome after out-of-hospital cardiac arrest: results of the AfterROSC1 multicentric study

Ann Intensive CarePublished Prospective multicentre prognostic study

Authors' conclusion

In patients admitted to ICUs after a successfully resuscitated OHCA, most of the scores available for the evaluation of the subsequent prognosis are more efficient than the usual Utstein criteria but calibration is unacceptable for some of them.

Study context

Population
Comatose (GCS ≤ 8) patients with non-traumatic out-of-hospital cardiac arrest (OHCA) and stable return of spontaneous circulation (ROSC) admitted to 24 French and Belgian Intensive Care Units (ICUs), August 2020–June 2022907 screened
Participants
658 participants
Comparison
Dedicated prognostic scores vs Utstein style criteria
Outcome
Modified Rankin scale (mRS) assessed by phone interview
Follow-up
Day 90 after cardiac arrest

Performance

As reported in the abstract

Poor outcome prediction (AUROC) · day 90
Test or modelValueAUROCAUROC range
Utstein criteria0.79 (CI 0.76–0.83)0.79
Other scores0.79 [0.75-0.83] to 0.88 [0.86-0.91]0.79 [0.75-0.83] to 0.88 [0.86-0.91]

Value

Utstein criteria0.79 (CI 0.76–0.83)
Other scores0.79 [0.75-0.83] to 0.88 [0.86-0.91]

AUROC

Utstein criteria0.79
Other scores— not stated in the abstract

AUROC range

Utstein criteria— not stated in the abstract
Other scores0.79 [0.75-0.83] to 0.88 [0.86-0.91]

Further findings

Mortality and unfavorable neurological outcome · day 90

Mortality rate
63%
Unfavorable neurological outcomes
66%

Proportion of patients for whom score could not be calculated

Range across scores
1.4% to 17.4%

Original publication

Prospective comparison of prognostic scores for prediction of outcome after out-of-hospital cardiac arrest: results of the AfterROSC1 multicentric study. Ann Intensive Care. Published 11 October 2023. doi:10.1186/s13613-023-01195-w

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