Sepsis & infection

Fluid management in sepsis associated acute kidney injury

J Crit CarePublished Narrative review

Authors' conclusion

A major limitation is that most fluid studies were conducted in critically ill patients in general, rather than patients with SA-AKI.

Study context

Population
Critically ill patients with sepsis-associated AKI (sepsis-associated acute kidney injury (SA-AKI))

Main finding

As reported in the abstract

  • Review covers the phases of fluid therapy, fluid management strategies in SA-AKI, preferred fluid types in different phases, and pharmacologic and mechanical fluid removal
  • Individualised strategies for specific subsets (septic cardiomyopathy, CKD) remain challenging
  • Most fluid studies were conducted in critically ill patients in general, not in SA-AKI

Original publication

Fluid management in sepsis associated acute kidney injury. J Crit Care. Published 22 July 2025. doi:10.1016/j.jcrc.2025.155188

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