Respiratory failure & ventilation
Frequency-domain band-pass filtering enhanced pulsation method for pulmonary embolism diagnosis and risk stratification: a two-center retrospective study
Authors' conclusion
MI, DI, and SI differentiated PE patients from healthy controls, while MI and DI were associated with risk stratification.
Study context
- Population
- Pulmonary embolism (PE) patients and healthy controls assessed with frequency-domain band-pass filtering enhanced electrical impedance tomography (EIT) pulsation method
- Participants
- 106 patients · 2 centres
- Comparison
- PE patients vs healthy controls
- PEn = 53
- Healthy controlsn = 53reference
- Outcome
- EIT-derived parameters, PE vs healthy controls
Methodological detailstwo-centre
- Two-centre
Performance
As reported in the abstract
- PE vs Healthy controls: P < 0.001
- PE vs Healthy controls: P < 0.001
- PE vs Healthy controls: P = 0.005
Further findings
Risk stratification (intermediate-high-risk vs lower-risk PE)
- Intermediate-high-risk PE: lower Matching Index (MI) and higher DI than lower-risk; strongest vs low-risk (both adjusted P < 0.001)
Diagnostic discrimination, combined MI + DI+Shunt Index (SI) model
- AUC (95% CI: 0.741-0.899); highest among EIT parameters, marginal improvement over MI alone, outperformed DI and SI
- 0.820
- EIVQ showed no significant discriminative value
Original publication
Frequency-domain band-pass filtering enhanced pulsation method for pulmonary embolism diagnosis and risk stratification: a two-center retrospective study. Crit Care. Published 10 July 2026. doi:10.
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